How a nano-vesicle
teaches your brain to
rebuild itself.
30-150 nm vesicles carrying miRNA cargo. Delivered intranasally, they bypass the BBB and reach the CNS in minutes.
An exosome is a signed envelope.
A lipid bilayer studded with tetraspanins CD9, CD63, CD81 — a molecular signature that says: trust this, and open it.
Inside: miRNA, mRNA, and signaling proteins from a young, regenerative parent stem cell.
The nose is the back door to the brain.
The olfactory epithelium is the only place where the CNS meets the outside world without an intervening blood vessel. Molecules travel olfactory and trigeminal fibers across the cribriform plate directly into brain parenchyma.
One 100 µL spray delivers 5×10⁹ exosomes. Distribution to olfactory bulb, prefrontal cortex, and hippocampus within the hour.
Six steps from spray to restored neuron.
- 1Deposition
Exosomes settle onto the olfactory epithelium after a single 100 µL spray.
- 2Axonal transit
Vesicles travel along olfactory and trigeminal nerve fibers through the cribriform plate into the CNS.
- 3Docking & fusion
Surface tetraspanins recognize receptors on neurons, microglia, and neural stem cells. Membranes fuse.
- 4miRNA release
The exosome opens into the cytoplasm and releases its curated microRNA payload.
- 5Silencing senescence
miRNA loads into the RISC complex and silences transcripts driving neuroinflammation and cellular aging.
- 6Neurogenic reactivation
Freed regenerative transcripts translate. Synaptogenesis, mitochondrial biogenesis, and stem-cell-niche activity resume.
Not a drug. Not a supplement. A conversation.
Signal doesn't ask permission of the BBB — it takes the anatomical loophole nature already provides. A brain that behaves younger, not one that's been drugged.